Protein FLICE-i ( bahasa Inggris : FLICE-inhibitory protein, CASP8 and FADD-like apoptosis regulator, FADD-like IL-1beta-converting enzyme inhibitory protein, FLIP ) adalah faktor transkripsi dengan berkas genetik CFLAR pada kromosom 2 lokasi 2q33-q34, [ 1 ] yang banyak terdapat pada jaringan otot dan , [ 2 ] sebagai regulator apoptosis .
Overekspresi FLIP dapat melindungi sel tumor dari mekanisme apoptosis . [ 3 ]
Rujukan
- ^ (Inggris) "CFLAR CASP8 and FADD-like apoptosis regulator [ Homo sapiens ]" . Entrez Gene . Diakses tanggal 2010-10-26 .
- ^ (Inggris) "Inhibition of death receptor signals by cellular FLIP" . Institute of Biochemistry, Lausanne branch, University of Lausanne; Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J . Diakses tanggal 2010-10-26 .
- ^ (Inggris) "The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer" . Cancer Research UK Institute for Cancer Studies, Division of Cancer Studies, Department of Pathology, The Medical School, University of Birmingham; Dutton A, Young LS, Murray PG . Diakses tanggal 2010-10-26 .
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